HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Hikaru Sugimoto Selected Research

acetoxycycloheximide

2/2009Caspase-8 mediates mitochondrial release of pro-apoptotic proteins in a manner independent of its proteolytic activity in apoptosis induced by the protein synthesis inhibitor acetoxycycloheximide in human leukemia Jurkat cells.
6/2008ERK and p38 MAP kinase are involved in downregulation of cell surface TNF receptor 1 induced by acetoxycycloheximide.
4/2008Ectodomain shedding of TNF receptor 1 induced by protein synthesis inhibitors regulates TNF-alpha-mediated activation of NF-kappaB and caspase-8.
2/2005Acetoxycycloheximide (E-73) rapidly induces apoptosis mediated by the release of cytochrome c via activation of c-Jun N-terminal kinase.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Hikaru Sugimoto Research Topics

Disease

22Neoplasms (Cancer)
01/2020 - 04/2003
8Fibrosis (Cirrhosis)
09/2015 - 07/2007
6Neoplasm Metastasis (Metastasis)
12/2018 - 09/2011
5Kidney Diseases (Kidney Disease)
01/2021 - 08/2002
5Inflammation (Inflammations)
01/2018 - 07/2007
5Proteinuria
04/2007 - 11/2002
4Carcinoma (Carcinomatosis)
01/2022 - 12/2006
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2022 - 11/2015
4Pre-Eclampsia (Preeclampsia)
11/2018 - 04/2003
3Renal Insufficiency (Renal Failure)
06/2021 - 07/2005
3Breast Neoplasms (Breast Cancer)
01/2020 - 11/2014
3Hypoxia (Hypoxemia)
01/2020 - 10/2005
3Carcinogenesis
10/2018 - 06/2011
3Hereditary Nephritis (Alport Syndrome)
11/2009 - 04/2005
3Diabetic Nephropathies (Diabetic Nephropathy)
12/2008 - 09/2002
2Hypertension (High Blood Pressure)
08/2022 - 11/2018
2Adenocarcinoma
12/2021 - 11/2015
2Nephritis
06/2021 - 11/2002
2IgA Vasculitis (Purpura, Schoenlein Henoch)
06/2021 - 01/2021
2Diabetes Complications
01/2011 - 07/2007
2Leukemia
02/2009 - 02/2005
2Glomerulonephritis
03/2008 - 11/2002
1Wounds and Injuries (Trauma)
01/2022
1Osteogenesis Imperfecta (Lobstein Disease)
12/2021
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2021
1Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
01/2021
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2018
1Liver Diseases (Liver Disease)
01/2018

Drug/Important Bio-Agent (IBA)

7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2011 - 04/2003
7type IV collagen alpha3 chain (Goodpasture antigen)IBA
06/2011 - 04/2003
6Proteins (Proteins, Gene)FDA Link
05/2014 - 04/2003
6Collagen Type IV (Type IV Collagen)IBA
11/2009 - 04/2005
5CollagenIBA
02/2013 - 06/2003
4Collagen Type I (Type I Collagen)IBA
01/2022 - 12/2006
4Angiogenesis InhibitorsIBA
06/2011 - 03/2004
4EndostatinsIBA
06/2011 - 04/2003
4acetoxycycloheximideIBA
02/2009 - 02/2005
3IntegrinsIBA
01/2022 - 06/2003
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2018 - 06/2008
3Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
11/2018 - 02/2005
3Transforming Growth Factors (Transforming Growth Factor)IBA
10/2018 - 06/2010
3AntibodiesIBA
02/2013 - 04/2003
3Peptides (Polypeptides)IBA
02/2012 - 09/2008
3Streptozocin (Streptozotocin)FDA Link
01/2011 - 07/2007
2Indicators and Reagents (Reagents)IBA
08/2022 - 12/2018
2Adrenal Cortex Hormones (Corticosteroids)IBA
06/2021 - 01/2021
2Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
11/2018 - 06/2008
2Small Interfering RNA (siRNA)IBA
01/2018 - 01/2017
2Angiopoietin-2IBA
12/2016 - 02/2015
2GemcitabineFDA Link
11/2015 - 06/2014
2Biological ProductsIBA
02/2015 - 02/2013
2Protein Synthesis InhibitorsIBA
02/2009 - 06/2008
2Caspase 8 (Caspase-8)IBA
02/2009 - 04/2008
2Integrin alpha1IBA
11/2008 - 10/2005
2Integrin alphaVbeta3IBA
09/2008 - 02/2005
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2008 - 04/2003
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2008 - 04/2008
2NF-kappa B (NF-kB)IBA
06/2008 - 04/2008
2nephrinIBA
04/2007 - 04/2003
2Thrombospondin 1IBA
02/2005 - 03/2004
2Matrix Metalloproteinases (MMPs)IBA
03/2004 - 06/2003
1Antihypertensive Agents (Antihypertensives)IBA
08/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Azathioprine (Imuran)FDA LinkGeneric
06/2021
1SteroidsIBA
06/2021
1Antisense OligonucleotidesIBA
01/2021
1mizoribineIBA
01/2021
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2021
1Immunoglobulin A (IgA)IBA
01/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1Fatty Acids (Saturated Fatty Acids)IBA
01/2020
1Pyruvic Acid (Pyruvate)IBA
01/2020
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1Oxygen (Dioxygen)IBA
01/2020
1Glucose (Dextrose)FDA LinkGeneric
01/2020
1Prostaglandins FIBA
11/2018
1GlycogenIBA
11/2018
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
10/2018
1Transforming Growth Factor-beta Type II ReceptorIBA
10/2018
1Calcium-Binding ProteinsIBA
01/2018
1Ganciclovir (Cytovene)FDA LinkGeneric
01/2018
1nasIBA
01/2018
1GTP Phosphohydrolases (GTPases)IBA
01/2017
1Paclitaxel (Taxol)FDA LinkGeneric
12/2016
1Epirubicin (Ellence)FDA LinkGeneric
12/2016
1NucleosidesIBA
11/2015
1AngiopoietinsIBA
02/2015
1MicroRNAs (MicroRNA)IBA
11/2014
1DisulfidesIBA
02/2013
1Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
02/2013
1Serine Proteases (Serine Protease)IBA
02/2013
1Biomarkers (Surrogate Marker)IBA
02/2013
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
02/2012
1Captopril (Capoten)FDA LinkGeneric
02/2012
1Activins (Activin)IBA
02/2012
1Phosphotransferases (Kinase)IBA
02/2012

Therapy/Procedure

10Therapeutics
01/2022 - 11/2002
2Drug Therapy (Chemotherapy)
12/2016 - 11/2015
2Transplantation
11/2009 - 05/2006
1Immunotherapy
06/2014